49ers' top plays from 2005 Mexico game vs. Cardinals | NFL Throwback

Drafted on each end of the spectrum, these QBs went head-to-head in win-or-go-home games. Find out who prevailed in each instance.

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From last-second heartbreaks to monumental upsets, these are the most brutal ways to lose in the playoffs.

Listen to the greatest mic'd up and press conference sound from Bill Belichick's legendary tenure with the New England Patriots.

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From Barry Sanders to Johnny Manziel, find out how each Heisman winner fared at the next level.

Watch as teams try to complete the impossible! Spoiler alert: they all fall just short.

From Randy Moss' three-TD day to Leon Lett's costly moment, catch up on all the memorable Thanksgiving football highlights from over the years.

A Chicago legend and one of the greatest running backs ever to lace 'em up -- no one could do it quite like "Sweetness."

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Watch the wildest back-and-forth games in NFL history.

A savant at the middle linebacker position -- relive the moments that made Patrick Willis' illustrious career one to remember.

It may not always look pretty on the stat sheet, but these teams accomplished the only thing that matters -- getting the win.

From All-Pros to MVPs and Super Bowl champions, NFL Throwback takes another deep dive into the most underrated players in history.

Experience touchdown after touchdown in this video highlighting the most explosive scoring outputs we've seen in the modern era.

Relive the most ridiculous plays from one of the original dual-threat QBs.

From Jim Brown to Randy Moss, take a look back at the most dominant rookie campaigns in NFL history.

Check out the most exciting game-winning kick and punt returns in NFL history.