Can't-Miss Play: Guerendo's 76-yard scamper puts icing on 49ers' 'TNF' win in Seattle

San Francisco 49ers rookie running back Isaac Guerendo saves his career-long rush for the perfect time as he races 76 yards to put icing on the 49ers' "Thursday Night Football" win over the Seattle Seahawks

Seattle Seahawks wide receiver Laviska Shenault Jr.'s 97-YARD touchdown on a kickoff return sends the Lumen Field crowd into a frenzy.

San Francisco 49ers wide receiver Deebo Samuel Sr. breaks free for a 76-yard touchdown on quarterback Brock Purdy's launch downfield.

Big-man INT! New Orleans Saints defensive tackle Khalen Saunders rumbles 35 yards after a HUGE defensive play.

43-yard touchdown! New Orleans Saints quarterback Derek Carr fires deep to wide receiver Rashid Shaheed to put six on the board for the Saints.

Dallas Cowboys quarterback Dak Prescott's CLUTCH fourth-down touchdown to Jalen Tolbert ices his team's 'Sunday Night Football' win over the Pittsburgh Steelers.

New York Giants linebacker Isaiah Simmons comes right through the middle of the Seattle Seahawks field goal team to block a game-tying kick off the foot of Seahawks kicker Jason Myers, and Giants wide receiver Bryce Ford-Wheaton returns it for a game-sealing touchdown.

Las Vegas Raiders tight Jakobi Meyers' toe-tap catch offers cinematic ending to quarterback Aidan O'Connell's sideline dime.

Arizona Cardinals Kyler Murray magic! Kyler and wide receiver Marvin Harrison Jr. team up for pivotal conversion vs. San Francisco 49ers.

New York Giants quarterback Daniel Jones and wide receiver Darius Slayton connect for the second time on the same drive, this time for a 30-yard touchdown that gives the Giants a 16-10 lead vs. the Seattle Seahawks.

Can't-Miss Play: Pick-six touchdown! Los Angeles Rams rookie safety Jaylen McCollough turns Green Bay Packers quarterback Jordan Love's pass into a score for the Rams

San Francisco 49ers defensive end Nick Bosa's first interception since 2019 comes vs. Arizona Cardinals quarterback Kyler Murray.

Los Angeles Rams wide receiver Demarcus Robinson's spectacular 16-yard grab comes with mid-air acrobatics.

61-yard touchdown! San Francisco 49ers cornerback Deommodore Lenoir scoops a loose ball for the score after Jordan Elliott's FG block.

Green Bay Packers quarterback Jordan Love's 53-yard launch dots Packers wide receiver Jayden Reed amid three Los Angeles Rams defenders in nearby position.

On a 4th-and-goal run, New York Giants running back Eric Gray reaches for the goal line and fumbles leading to Seattle Seahawks defensive back Rayshawn Jenkins picking up the loose ball and returning it 102 yards for a touchdown, the longest return touchdown in Seattle Seahawks franchise history.

Denver Broncos cornerback Pat Surtain II intercepts a pass from Raiders quarterback Gardner Minshew and returns it for a 100-yard touchdown.

Baltimore Ravens running back Derrick Henry's 51-yard dash burns Cincinnati Bengals in overtime.

Announcer Kevin Harlan goes wild over Cincinnati Bengals' takeaway vs. Baltimore Ravens in overtime.

50-yard touchdown run! Arizona Cardinals quarterback Kyler Murray burns San Francisco 49ers defense for six at Levi's.

Houston Texans kicker Ka'imi Fairbairn is perfect on a 59-yard game-winning field goal against the Buffalo Bills.

Las Vegas Raiders tight end Brock Bowers catches a 57-yard touchdown catch from quarterback Gardner Minshew vs. Denver Broncos.

65-yard touchdown! Indianapolis Colts quarterback Joe Flacco and wide receiver Alec Pierce put team on their back against the Jacksonville Jaguars.

Baltimore Ravens quarterback Lamar Jackson completes an incredible touchdown pass to tight end Isaiah Likely.

Indianapolis Colts wide receiver Alec Piece looks like peak Odell Beckham Jr. on one-handed catch vs the Jacksonville Jaguars.