Patrick Mahomes' best plays from 352-yard game vs. Colts | Week 12

Watch the best plays from Kansas City Chiefs quarterback Patrick Mahomes' 352-yard game against the Indianapolis Colts in Week 12 of the 2025 NFL season.

Highlights from Arizona Cardinals wide receiver Michael Wilson during Week 12 of the 2025 NFL season against the Jacksonville Jaguars where he posted 118 receiving yards in a valiant effort that unfortunately was not enough.

Highlights from the Week 12 performance of Jacksonville Jaguars quarterback Trevor Lawrence during the 2025 NFL season against the Arizona Cardinals where he threw 3 touchdown passes.

Highlights from Jacksonville Jaguars running back Travis Etienne's Week 12 performance against the Arizona Cardinals in the 2025 NFL season where he amassed 116 yards from scrimmage.

Watch Philadelphia Eagles quarterback Jalen Hurts' best plays from a 3-touchdown, 322-yard game against the Dallas Cowboys from Week 12 of the 2025 NFL season.

Watch every catch from Philadelphia Eagles wide receiver A.J. Brown's 110-yard game against the Dallas Cowboys from Week 12 of the 2025 NFL season.

Watch every catch from Dallas Cowboys wide receiver George Pickens' 146-yard game against the Philadelphia Eagles from Week 12 of the 2025 NFL season.

Watch the best plays from Dallas Cowboys quarterback Dak Prescott's 3-touchdown, 365-yard game against the Philadelphia Eagles from Week 12 of the 2025 NFL season.

Watch the best plays from Las Vegas Raiders running back Ashton Jeanty's 108-yard game against the Cleveland Browns in Week 12 of the 2025 NFL season.

Watch the best plays from the Cleveland Browns' defense against the Las Vegas Raiders in Week 12 of the 2025 NFL season.

See every touch from Cleveland Browns rookie quarterback Shedeur Sanders' first start against the Las Vegas Raiders in Week 12 of the 2025 NFL season.

New England Patriots tight end Hunter Henry's best plays from his 115-yard game vs. the Cincinnati Bengals during Week 12 of the 2025 NFL season.

Detroit Lions wide receiver Amon-Ra St. Brown's best plays in his 149-yard game vs. the New York Giants during Week 12 of the 2025 NFL season.

Detroit Lions running back Jahmyr Gibbs' best plays in his 129-yard game vs. the New York Giants during Week 12 of the 2025 NFL season.

Watch every New York Giants wide receiver Wan'Dale Robinson catch in 156-yard game during Week 12 of the 2025 NFL season.

Chicago Bears wide receiver DJ Moore caught a pair of touchdowns in his team's Week 12 win over the Pittsburgh Steelers.

Watch the best plays by New York Giants quarterback Jameis Winston's best plays in 3-TD game during Week 12 of the 2025 NFL season.

Pittsburgh Steelers running back Kenneth Gainwell combined for 122 yards in Week 12 against the Chicago Bears.

Watch the best plays from Kansas City Chiefs wide receiver Rashee Rice's 141-yard game against the Indianapolis Colts in Week 12 of the 2025 NFL season.

Chicago Bears quarterback Caleb Williams posted a 104.3 quarterback rating with three touchdown passes in the team's Week 12 win over the Pittsburgh Steelers.

Highlights from the impressive outing by the Green Bay Packers' defensive unit against the Minnesota Vikings during Week 12 of the 2025 NFL season.

Highlights from Green Bay Packers running back Emanuel Wilson during Week 12 of the 2025 NFL season where he scored twice to ensure Green Bay's victory over the Minnesota Vikings.

Watch Seattle Seahawks wide receiver Jaxon Smith-Njigba's best plays from his 171-yard, 2-touchdown game vs. the Tennessee Titans in Week 12 of the 2025 NFL season.

The Houston Texans' best defensive plays from their 8-sack game against the Buffalo Bills in Week 12 of the 2025 NFL season.

Buffalo Bills wide receiver Khalil Shakir's best plays in his 110-yard game vs. the Houston Texans during Week 12 of the 2025 NFL season.