Peyton breaks down Devin Lloyd's pick-six on Mahomes | 'ManningCast'

On the "ManningCast," Pro Football Hall of Fame quarterback Peyton Manning gives an in-depth breakdown of Jacksonville Jaguars linebacker Devin Lloyd's 99-yard pick-six off Kansas City Chiefs quarterback Patrick Mahomes.

Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning are joined by San Francisco 49ers linebacker Fred Warner as they react to Jacksonville Jaguars quarterback Trevor Lawrence completing a clutch 33-yard pass to wide receiver Brian Thomas Jr.

San Francisco 49ers linebacker Fred Warner, Pro Football Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning react to Jacksonville Jaguars quarterback Trevor Lawrence's game-winning touchdown run.

San Francisco 49ers linebacker Fred Warner reacts to Pro Football Hall of Fame quarterback Peyton Manning's hypothetical new rule proposals.

On the "ManningCast", San Francisco 49ers linebacker Fred Warner praises Kansas City Chiefs quarterback Patrick Mahomes after his unbelievable escape to turn would-be sack into first down.

San Francisco 49ers linebacker Fred Warner joins Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning on the 'ManningCast of MNF with Peyton and Eli'.

Pro Football Hall of Fame quarterback Peyton Manning takes a closer look at Kansas City Chiefs cornerback Trent McDuffie's interception on Jacksonville Jaguars quarterback Trevor Lawrence.

On the 'ManningCast of MNF with Peyton and Eli' Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning are joined by actress Heidi Gardner who compares the joy of super bowl victories.

Actress and comedian Heidi Gardner reacts to Jacksonville Jaguars linebacker Devin Lloyd's 99-yard interception of Kansas City Chiefs quarterback Patrick Mahomes for a touchdown.

Actress and comedian Heidi Gardner joins Pro Football Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning on the "ManningCast" to talk about her hometown team, the Kansas City Chiefs.

On the 'ManningCast of MNF with Peyton and Eli' Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning react to the 10-yard touchdown scramble by Jacksonville Jaguars quarterback Trevor Lawrence.

Pro Football Hall of Fame quarterback Peyton Manning gives high praise to Jacksonville Jaguars quarterback Trevor Lawrence after his touchdown pass to wide receiver Parker Washington.

On "ManningCast", Pro Football Hall of Fame quarterback Peyton Manning gives an in-depth breakdown of the play design of Jacksonville Jaguars quarterback Trevor Lawrence's 3-yard touchdown pass to wide receiver Parker Washington.

On the 'ManningCast of MNF with Peyton and Eli' Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning are joined by actor Glen Powell.

On the 'ManningCast of MNF with Peyton and Eli' Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning reminisce about a teenage Kansas City Chiefs quarterback Patrick Mahomes as a camper at Peyton's youth passing camps.

On "ManningCast", Pro Football Hall of Fame quarterback Peyton Manning breaks down Kansas City Chiefs quarterback Patrick Mahomes' 32-yard completion to wide receiver Tyquan Thornton, highlighting Thornton's smart adjustment to come back to the ball and make the huge play.

Former NFL quarterback Eli Manning talks with Hall of Fame quarterback Peyton Manning about his various undercover adventures during the offseason on the 'ManningCast' of "Monday Night Football".

On "ManningCast", Pro Football Hall of Fame quarterback Peyton Manning praised the Detroit Lions and their head coach Dan Campbell for sticking to their identity despite losing their offensive and defensive coordinators last offseason.

Pro Football Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning react to the Detroit Lions gutsy 4th-down play call that resulted in wide receiver Amon-Ra St. Brown hauling in a 20-yard catch.

Pro Football Hall of Fame quarterback Peyton Manning, former NFL quarterback Eli Manning and 23-time Olympic Gold Medalist Michael Phelps react to the Detroit Lions' 4-yard trick-play touchdown from Jahmyr Gibbs.

U.S.A. gold medalist and olympic legend Michael Phelps talks with Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning about the possibilities of choosing football over swimming in his high school days on the 'ManningCast'.

Gold medalist and Baltimore native Michael Phelps stops by the 'ManningCast' of "Monday Night Football" to talk all things Baltimore.

Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning detail a sequence by Baltimore Ravens quarterback Lamar Jackson and tight end Mark Andrews, leading to a Ravens touchdown on the "ManningCast' of "Monday Night Football".

On "ManningCast", Pro Football Hall of Fame quarterback Peyton Manning and former NFL quarterback Eli Manning replicate the usual offensive coordinator-quarterback phone call that would take place after a touchdown drive.

On the "ManningCast' on 'Monday Night Football', Hall of Fame quarterback Peyton Manning jokes with Indianapolis Colts quarterback Daniel Jones about the difference in media attention he received as opposed to the attention former NFL quarterback Eli Manning received in New York.