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(NOTE: Teams listed in alphabetical order.)
- QB David Blough (from Vikings practice squad)
- QB Carson Strong (to practice squad)
- TE Maxx Williams (to active roster from practice squad)
- CB Jace Whittaker
- DT Anthony Rush (to practice squad)
- CB Trayvon Mullen claimed, NFL Network Mike Garafolo reported, per Mullen's agent.
- LB Malik Jefferson (from practice squad)
- QB Russell Wilson remains in concussion protocol and did not practice Wednesday, per head coach Nathaniel Hackett.
- FB/TE Andrew Beck (hamstring) limited
- WR Courtland Sutton (hamstring) DNP
- WR Kendall Hinton (hamstring) DNP
- DE Jake Martin (knee) placed on injured reserve.
- NT D.J. Jones (shoulder) full
- LB Randy Gregory's 21-day practice window to return from injured reserve is open. Denver is hopeful Gregory can return Sunday against Arizona.
- CB K'Waun Williams (wrist/knee) limited
- K Brandon McManus (quad) limited
- RB Dameon Pierce (ankle) did not practice Wednesday.
- WR Jalen Camp placed on practice squad injured list
- WR Nico Collins (foot) DNP
- WR Brandin Cooks (calf) DNP
- OL Jordan Steckler designated to return from practice squad injured list
- OL Laremy Tunsil (illness) DNP
- DB Steven Nelson (foot) DNP
- DB Derek Stingley Jr. (hamstring) DNP
- QB Patrick Mahomes (right hand) was a full participant in practice Wednesday.
- WR Mecole Hardman (adbomen) returned to practice Wednesday. Hardman was placed on injured reserve on Nov. 17.
- RB Isiah Pacheco (shoulder/quad) full
- WR JuJu Smith-Schuster (toe) full
- WR Kadarius Toney (hamstring) limited
- OT Lucas Niang (knee) full
- LB Nick Bolton (groin) full
- CB L'Jarius Sneed (calf) full
- S Justin Reid (shoulder) full
- RB Damien Harris (thigh), limited
- RB Rhamondre Stevenson (ankle) DNP
- WR Jakobi Meyers (concussion) limited
- OL Isaiah Wynn (foot) DNP
- CB Jalen Mills (groin) limited
- RB Mark Ingram (knee) did not practice Wednesday.
- TE Juwan Johnson (ankle) limited
- OT Ryan Ramczyk (rest/knee) limited
- DE Cameron Jordan (foot) limited
- DE Payton Turner (ankle) limited
- LB Zack Baun (ankle) DNP
- LB Pete Werner (ankle) limited
- CB Marshon Lattimore (abdomen) limited
- S P.J. Williams (knee) DNP
- K Wil Lutz (illness) DNP
- DT Jonathan Marshall (from Jets practice squad)
- WR Julio Jones (knee) did not participate in practice Wednesday.
- OT Tristan Wirfs (ankle) DNP
- NT Vita Vea (calf) DNP
- LB Carl Nassib (pectoral) DNP
- LB Joe Tryon-Shoyinka (hip) limited
- CB Jamel Dean (toe) DNP
- CB Sean Murphy-Bunting (quad) full
- S Mike Edwards (hamstring) limited
- S Antoine Winfield Jr. (ankle) limited
- QB Ryan Tannehill (ankle) was a limited participant in practice Wednesday.
- WR Treylon Burks (concussion) DNP
- WR Robert Woods (illness) DNP
- C Ben Jones (neck) limited
- DT Jeffery Simmons (ankle) limited
- LB Denico Autry (knee) limited
- CB Kristian Fulton (groin) DNP
- S Amani Hooker (knee) limited
- LB Zach Cunningham designated to return from injured reserve